Cyclosporin A (CyA) has been used successfully in the treatment of rheumatoid arthritis. There is one case report of CyA used successfully in the treatment of severe systemic onset Still's disease. To our knowledge, there are no reports of CyA used in adult Still's disease. We present the first report of a patient with refractory adult Still's disease successfully treated with CyA. We submit that cyclosporine treatment may induce remission of symptoms in patients with adult Still's disease and reduce the steroid requirements.