Abstract
In this double blind, crossover trial, 40 patients with ankylosing spondylitis were treated during two successive periods of 4 weeks each with either pirprofen 800 mg/day or ketoprofen 300 mg/day administered orally in a randomized order. The efficacy of pirprofen and ketoprofen was comparable, the results, as assessed by the clinician, were excellent or satisfactory in 53% of both groups. Pirprofen was well tolerated by 71% of the patients and ketoprofen by 59%.
Publication types
-
Clinical Trial
-
Comparative Study
-
English Abstract
-
Randomized Controlled Trial
MeSH terms
-
Adult
-
Anti-Inflammatory Agents / adverse effects
-
Anti-Inflammatory Agents / therapeutic use*
-
Clinical Trials as Topic
-
Double-Blind Method
-
Female
-
Humans
-
Ketoprofen / adverse effects
-
Ketoprofen / therapeutic use*
-
Male
-
Phenylpropionates / adverse effects
-
Phenylpropionates / therapeutic use*
-
Spondylitis, Ankylosing / drug therapy*
Substances
-
Anti-Inflammatory Agents
-
Phenylpropionates
-
Ketoprofen
-
pirprofen