JAKs and STATs in immunity, immunodeficiency, and cancer

N Engl J Med. 2013 Jan 10;368(2):161-70. doi: 10.1056/NEJMra1202117.
No abstract available

Publication types

  • Review

MeSH terms

  • Cytokines / metabolism
  • Hematologic Diseases / drug therapy
  • Hematologic Diseases / genetics
  • Hematologic Diseases / physiopathology
  • Humans
  • Immunologic Deficiency Syndromes / drug therapy
  • Immunologic Deficiency Syndromes / genetics*
  • Immunologic Deficiency Syndromes / physiopathology
  • Janus Kinases / antagonists & inhibitors
  • Janus Kinases / genetics
  • Janus Kinases / metabolism*
  • Mutation
  • Neoplasms / drug therapy
  • Neoplasms / genetics*
  • Neoplasms / physiopathology
  • STAT Transcription Factors / genetics
  • STAT Transcription Factors / metabolism*
  • Signal Transduction / drug effects

Substances

  • Cytokines
  • STAT Transcription Factors
  • Janus Kinases