Cytokines as therapeutic targets: advances and limitations

Immunity. 2008 Apr;28(4):440-4. doi: 10.1016/j.immuni.2008.03.005.

Abstract

Biological therapies targeting cytokines, T cells, or B cells have improved outcomes of inflammatory diseases. However, many issues remain open: What is the best target? How well can response be predicted? How can cure be achieved?

Publication types

  • Review

MeSH terms

  • Arthritis, Rheumatoid / diagnosis
  • Arthritis, Rheumatoid / immunology*
  • Arthritis, Rheumatoid / pathology
  • Arthritis, Rheumatoid / therapy*
  • Cytokines / antagonists & inhibitors*
  • Cytokines / physiology*
  • Drug Delivery Systems / adverse effects
  • Drug Delivery Systems / methods*
  • Drug Delivery Systems / trends*
  • Humans
  • Immunity, Cellular / drug effects
  • Immunity, Cellular / immunology*
  • Randomized Controlled Trials as Topic

Substances

  • Cytokines