Abstract
The details of a patient with disseminated scleromyxedema related to multiple myeloma are presented. Investigation demonstrated extensive accumulation of mucopolysaccharides in the skin, bone marrow and the small bowel submucosa. The latter finding is a most unusual manifestation of scleromyxedema and appeared to correlate with the patient's symptoms on presentation.
MeSH terms
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Aged
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Biopsy
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Bone Marrow / chemistry
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Diarrhea / etiology
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Female
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Glycosaminoglycans / analysis
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Humans
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Intestinal Diseases / complications*
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Intestinal Diseases / pathology
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Intestine, Small / chemistry
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Intestine, Small / pathology*
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Multiple Myeloma / complications*
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Multiple Myeloma / pathology
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Myxedema / complications*
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Myxedema / pathology
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Skin / chemistry
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Weight Loss