Abstract
Methotrexate, an antirheumatic drug that may increase serum homocysteine, significantly increases mortality in patients with rheumatoid arthritis and cardiovascular comorbidity.
MeSH terms
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Adult
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Aged
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Antirheumatic Agents / adverse effects*
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Antirheumatic Agents / therapeutic use
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Arteriosclerosis / epidemiology*
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Arteriosclerosis / mortality
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Arthritis, Rheumatoid / drug therapy*
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Arthritis, Rheumatoid / epidemiology*
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Arthritis, Rheumatoid / mortality
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Comorbidity
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Female
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Humans
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Male
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Methotrexate / adverse effects*
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Methotrexate / therapeutic use
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Middle Aged
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Retrospective Studies
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Survival Analysis
Substances
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Antirheumatic Agents
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Methotrexate