Evidence that anticardiolipin antibodies are independent risk factors for atherosclerotic vascular disease

C J Glueck; J E Lang; T Tracy; L Sieve-Smith; P Wang

doi:10.1016/s0002-9149(99)00130-7

Evidence that anticardiolipin antibodies are independent risk factors for atherosclerotic vascular disease

Am J Cardiol. 1999 May 15;83(10):1490-4, A8. doi: 10.1016/s0002-9149(99)00130-7.

Authors

C J Glueck¹, J E Lang, T Tracy, L Sieve-Smith, P Wang

Affiliation

¹ Cholesterol Center, Jewish Hospital, Cincinnati, Ohio 45229, USA. glueckch@healthall.com

PMID: 10335769
DOI: 10.1016/s0002-9149(99)00130-7

Abstract

Thrombophilic anticardiolipin antibodies (ACLAs) are independent risk factors for atherosclerotic vascular disease. We suggest that ACLAs IgG and IgM be routinely measured as ancillary atherothrombotic risk factors in all patients with atherosclerotic vascular disease events, in those at high risk for atherosclerotic vascular disease, and in those in whom thrombosis is a major pathoetiology.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Antibodies, Anticardiolipin / blood*
Arteriosclerosis / complications
Arteriosclerosis / immunology*
Cholesterol, HDL / blood
Cross-Sectional Studies
Female
Humans
Immunoglobulin G / blood*
Immunoglobulin M / blood*
Logistic Models
Male
Middle Aged
Odds Ratio
Risk Factors

Substances

Antibodies, Anticardiolipin
Cholesterol, HDL
Immunoglobulin G
Immunoglobulin M