Original ArticlePoststreptococcal Reactive Arthritis in Adults: A Case Series
Section snippets
Patients And Methods
After an inpatient or outpatient episode of care for all patients evaluated at Mayo Clinic Rochester, the final diagnoses are kept in an indexed database. We reviewed this established database for all adult patients evaluated from 1976 to 1998 who had a diagnosis of reactive streptococcal or streptococcus arthritis, arthralgia, or arthritides. The medical records of these patients were reviewed in detail to determine demographic data, antecedent streptococcal infection, laboratory evidence of
Patients
Thirty-five adults with the diagnosis of reactive streptococcal or streptococcus arthritis, arthralgia, or arthritides were initially identified. Of these, 7 patients met Jones criteria for acute rheumatic fever,63 had septic arthritis, and 19 lacked serologic evidence of antecedent streptococcal infection, which is necessary to make a definitive diagnosis of PSReA. Six patients (3 men and 3 women) met all the inclusion criteria. The clinical and laboratory data for these 6 patients are
Discussion
Goldsmith and Long7 first described PSReA in 1982. It was characterized as an illness of acute onset, usually coinciding with or following a recent streptococcal infection, with painful symmetric polyarthritis associated with high antistreptolysin 0 and streptozyme antibody titers. The diagnosis and treatment of 6 adult patients with PSReA are described in this case series.
The distinction between PSReA and ARF is not well defined in the medical literature. It has been suggested that PSReA and
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