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Eating bone or adding it: the Wnt pathway decides

Nature Medicine volume 13, pages 133–134 (2007)Cite this article

An inhibitor of the Wnt signaling pathway mediates bone destruction in inflammatory arthritis. The inhibitor may be the key to understanding why in some joint diseases bone is destroyed and in others built up (pages 156–163).

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Figure 1: Bifunctional role of the Wnt signaling pathway in regulation of osteoblast (bone-forming cell) and osteoclast (bone-resorbing cell) differentiation.

Katie Ris

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Authors and Affiliations

  1. the Research Division of the Hospital for Special Surgery, Weill College of Medicine of Cornell University, Caspary Research Building, 535 East 70th Street, New York, 10021, New York, USA

    Steven R Goldring & Mary B Goldring

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  1. Steven R Goldring
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  2. Mary B Goldring
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Goldring, S., Goldring, M. Eating bone or adding it: the Wnt pathway decides. Nat Med 13, 133–134 (2007). https://doi.org/10.1038/nm0207-133

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