Reviews and feature articlesAdvances in asthma, allergy mechanisms, and genetics in 2006
Section snippets
From genes to phenotypes and back: 1 year of asthma/allergy genetics in the journal
As recently discussed in these pages,21 allergic reactions involve multiple cellular and molecular interactions that ultimately converge to activate common effector mechanisms of disease. In addition to the classic players such as the TH2 inflammatory pathway, experimental allergy and clinical studies keep highlighting novel molecules and genes, each critical in the context of individual models. In the face of large numbers of studies and models, it is increasingly difficult to gauge the
References (44)
- et al.
Phosphoinositide 3-kinase-delta inhibitor reduces vascular permeability in a murine model of asthma
J Allergy Clin Immunol
(2006) - et al.
Immunostimulatory DNA inhibits allergen-induced peribronchial angiogenesis in mice
J Allergy Clin Immunol
(2006) - et al.
Remodeling associated expression of matrix metalloproteinase 9 but not tissue inhibitor of metalloproteinase 1 in airway epithelium: modulation by immunostimulatory DNA
J Allergy Clin Immunol
(2006) - et al.
Airway epithelial cells produce neurotrophins and promote the survival of eosinophils during allergic airway inflammation
J Allergy Clin Immunol
(2006) - et al.
Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma
J Allergy Clin Immunol
(2006) - et al.
IL-4 induces IL-13-independent allergic airway inflammation
J Allergy Clin Immunol
(2006) - et al.
Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals
J Allergy Clin Immunol
(2006) - et al.
Effects of established allergen sensitization on immune and airway responses after secondary allergen sensitization
J Allergy Clin Immunol
(2006) - et al.
Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses
J Allergy Clin Immunol
(2006) - et al.
IL-13 is essential to the late-phase response in allergic rhinitis
J Allergy Clin Immunol
(2006)
IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice
J Allergy Clin Immunol
Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma
J Allergy Clin Immunol
Downregulation of IgE antibody and allergic responses in the lung by epidermal biolistic microparticle delivery
J Allergy Clin Immunol
Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1alpha in allergic airway disease of mice
J Allergy Clin Immunol
Reversal of airway inflammation and remodeling in asthma by a bispecific antibody fragment linking CCR3 to CD300a
J Allergy Clin Immunol
Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice
J Allergy Clin Immunol
Reduced airway hyperresponsiveness and tracheal responses during allergic asthma in mice lacking tyrosine kinase inducible T-cell kinase
J Allergy Clin Immunol
Role of CCL21 and CCL19 in allergic inflammation in the ovalbumin-specific murine asthmatic model
J Allergy Clin Immunol
Activin A is an acute allergen-responsive cytokine and provides a link to TGF-beta-mediated airway remodeling in asthma
J Allergy Clin Immunol
Hierarchical suppression of asthma-like responses by mucosal tolerance
J Allergy Clin Immunol
Genetic regulation of IgE responses: Achilles and the tortoise
J Allergy Clin Immunol
The Faustian bargain of genetic association studies: bigger might not be better, or at least it might not be good enough
J Allergy Clin Immunol
Cited by (0)
Disclosure of potential conflict of interest: D. Vercelli served on the speakers' bureau for Merck. F. D. Finkelman has consultant arrangements with Amgen, Abbott, Plexxikon, Peptimmune, and Wyeth; has patent licensing arrangements with Becton-Dickinson and eBioscience; and has received research support from Amgen and Plexxikon.