Elsevier

Critical Care Clinics

Volume 22, Issue 1, January 2006, Pages 151-159
Critical Care Clinics

Dyslipidemia in the Critically Ill

https://doi.org/10.1016/j.ccc.2005.08.008Get rights and content

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      Alterations of lipid metabolism are frequent during critical illness, and hypertriglyceridemia is observed in nearly 45% of patients who require at least three days of ICU treatment.12 Hypertriglyceridaemia itself has been reported in PRIS,3 and there is a weak but significant association of high-fat diets in ICU patients with prolonged ventilation time.2 Furthermore, using a more concentrated 2% propofol solution could reduce fat overload.2

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      It has been proposed that MCTs, because of their rapid and rather complete oxidation, are associated with a lower risk of developing hyperTG than LCTs alone [9]. However, this hypothesis has remained controversial [21] probably because previous studies cited in the literature [9,12] had no clear TG baseline and investigated the incidence of hyperTG rather than changes in the TG profile. The small size of the studies and the low patient numbers may also explain the limited findings in the literature [8,22].

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