Natural autoantibodies: The other side of the immune system
References (116)
- et al.
Monoclonal, natural antibodies prevent development of diabetes in the non-obese diabetic (NOD) mouse
J. Autoimmun.
(1991) Natural autoantibodies: from “horror autotoxicus” to “gnothi seauton”
Immunol. Today
(1991)- et al.
The natural autoantibodies system: between hypotheses and facts
Mol. Immunol.
(1993) - et al.
Studies on natural antibodies and autoantibodies
Ann. Immunol. (Inst. Pasteur)
(1983) - et al.
Autoantibodies to cytokines friends or foes ?
Immunol. Today
(1990) - et al.
IgG auto-and polyreactivities of normal human sera
Mol. Immunol.
(1993) - et al.
Heat-labile serum inhibitor of anti-phospholipid antibody binding in ELISA
Immunol. Lett.
(1989) - et al.
Narural autoantibodies might prevent autoimmune disease
Immunol. Today
(1986) - et al.
Autoimmunity, microbial immunity and the immunological homunculus
Immunol. Today
(1991) The self/nonself discrimination: reconstructing a cabbage from sauerkraut
Res. Immunol.
(1992)
Modulation of autoimmunity by intravenous immuno-globulin through interaction with the function of the immune/idiotypic network
Clin. Immunol. Immunopathol.
Natural anti-TNP antibodies from rainbow trout interfere with viral infection in vitro
Res. Immunol.
Hypothesis. Autoantibodies and immunological theories: an analytical review
Clin. Immunol. Immunopathol.
Natural antibodies: origin, genetics, specificity and role in host resistance to tumours
Clin. Immunol. Allergy
Phagocytosis of keratin filament aggregates following opsonization with IgG-anti-keratin filament autoantibodies
J. Invest. Dermatol.
Natural antibodies and autoimmunity
Immunol. Today
Autoimmunity: the moving boundaries between physiology and pathology
J. Autoimmun.
A natural IgM antibody does inhibit polyclonal and antigen-specific IgM but not IgG B-cell responses
Immunol. Lett.
Natural autoantibodies in nude and normal outbred (Swiss) and inbred (BALB/c) mice
J. Autoimmun.
Negative selection of lymphocytes
Cell
Molecular mimicry and autoimmune disease
Cell
Transplantation of discordant xenografts: a review of progress
Immunol. Today
Heavy-chain directed B-cell maturation: continuous clonal selection beginning at the pre-B cell stage
Immunol. Today
The relationship between connectivity and tolerance as revealed by computer simulation of the immune network: some lessons for an understanding of autoimmunity
J. Autoimmun.
Autoantibodies and autoantigens: a conserved system that may shape a primary immuno-globulin gene pool
Mol. Immunol.
IgG autoantibody activity in normal mouse serum is controlled by IgM
J. Immunol.
Natural antibodies against bone marrow cells of a concordant xenogeneic species
J. Immunol.
Natural autoreactive B cells and autoantibodies: the "know thyself of the immune system
Ann. Immunol. (Inst. Pasteur)
Multispecific antibodies
Int. Rev. Immunol.
Méthode de marquage d'antigènes et d'anticorps avec des enzymes et son application en immuno-diffusion
C. R. Acad. Sci. (Paris)
Two murine natural polyreactive autoantibodies are encoded by nonmutated germline genes
Production of rheumatoid factor in adoptively immune guinea-pigs after challenge with Treponema pallidum
Immunology
Natural mouse IgG reacts with self antigens including molecules involved in the immune response
Eur. J. Immunol.
Les antihémolysines naturelles
Ann. Inst. Pasteur
B-cell repertoire in adult antigen-free and conventional neonatal BALB/c mice.-II. Analysis of antigen-binding capacities in relation to VH gene usage
Eur. J. Immunol.
Natural antibodies and the immune response
Adv. Immunol.
The clonal selection theory of acquired immunity
Autoantibody-mediated regulation of tumor growth
Ann. NY Acad. Sci.
CD5+ B lymphocytes, polyreactive antibodies and the human B-cell repertoire
Immunol. Today
Low natural antibody and low in vivo tumor resistance, in xid-bearing B-cell deficient mice
J. Immunol.
From an antigen-centered, clonal perspective of immune responses to an organism-centered, network perspective of autonomous activity in a selfreferential immune system
Immunol. Rev.
Beyond clonal selection and network
Immunol. Rev.
Speculations on immunosomatics: potential diagnostic and therapeutic value of immune homeostasis concepts
Scand. J. Immunol.
Natural antibodies to interferon-α and interferon-β are a common feature of inbred mouse strains
J. Immunol.
Murine hybridoma secreting natural monoclonal antibodies reacting with self antigens
J. Immunol.
B-cell tolerance and autoimmunity
Int. Rev. Exp. Pathol.
Nephritogenic autoantibodies in systemic lupus erythematosus: immunochemical properties, mechanisms of immune deposition, and genetic origins
Lab. Invest.
Excessive binding of natural anti-alpha-galactosyl immunoglobulin G to sickle erythrocytes may contribue to extra-vascular cell destruction
J. Clin. Invest.
A natural neonatal hybridoma autoantibody to the T200 antigen
J. Immunol.
Cleavage of supercoiled plasmid DNA by autoantibody Fab fragment: application of the flow linear dichroism technique
Cited by (86)
CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer
2022, Biochimica et Biophysica Acta - Reviews on CancerThe adaptive immune response to porous regenerated keratin as a bone graft substitute in an ovine model
2020, International Journal of Biological MacromoleculesCitation Excerpt :Following genetic recombination to create antibody diversity, those clones capable of autoreactivity are permanently deleted from the antibody repertoire (clonal selection and clonal deletion) [55]. Thus, the commonly held belief is that the presence of antibodies in serum capable of autoreactivity (autoantibodies) indicates an auto-immune (disease) state [56]. The presence of AKAs has been demonstrated in a range of human disease states [50,57], with IgG, IgA and IgM AKAs identified in normal human sera [45].
The origin and nature of the complex autoantibody profile in cerebrospinal fluid
2020, Brain, Behavior, and Immunity - HealthCitation Excerpt :In the past, the general consensus was that the appearance of autoantibodies (aABs) in the blood was a relatively rare event linked to some type of pathology, as was most clearly shown in various autoimmune diseases (Ippolito et al., 2011; Scott et al., 2010; Wanleenuwat and Iwanowski, 2019; Wielosz et al., 2014). More current research, however, now challenges the idea of central tolerance, with evidence supporting the ubiquitous presence of thousands of self-reactive aABs in the blood, even in the absence of pathology (Avrameas and Ternynck, 1995; Nagele et al., 2013). The idea of production of self-recognizing aABs in the absence of pathology supports a homeostatic role for this part of the immune system, including the response to sterile injury, immunosurveillance of cancer, facilitating wound resolution and tissue regrowth, and cell and tissue debris clearance.
On the origin of immunopathology
2015, Journal of Theoretical BiologyUtility of Autoantibodies as Biomarkers for Diagnosis and Staging of Neurodegenerative Diseases
2015, International Review of NeurobiologyCitation Excerpt :But further investigations proved that the phenomenon was widespread, involving antibodies that react to a multitude of intra- and extracellular autoantigens. These autoantibodies were identified in a variety of biological fluids, including blood, colostrum, saliva, and CSF (Avrameas, 1991; Avrameas & Ternynck, 1995; Bouvet & Dighiero, 1998). And they were identified in all tested mammals, including mice, rats, rabbits, pigs, and cows.