HLA-alloantigen associations in Greek patients with Sjögren's syndrome
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Genetics of Sjögren's syndrome
2017, Clinical ImmunologyCitation Excerpt :The authors confirmed HLA-DQA1 ∗ 001-DQA1 ∗ 0201-DQB1 ∗ 0501 in Israelite Jews and in Greeks HLA-DQA1 ∗ 050 [26]. Five years prior, HLA-DR5 was found to be one of the susceptibility genes in SS Greek patients [27], and in 2004 an extensive study examining Sjögren's syndrome associated with Systemic Lupus Erythematosus revealed that in these patients a high frequency of the HLA-DRB1*0301 allele was present [28]. Significant associations were also found in primary SS patients from southern Spain with HLA-Cw7, HLA-DR3 and HLA-DR11 [29].
Sjögren's Syndrome
2017, The Heart in Rheumatic, Autoimmune and Inflammatory Diseases: Pathophysiology, Clinical Aspects and Therapeutic ApproachesHLA and Sjögren's syndrome susceptibility. A meta-analysis of worldwide studies
2012, Autoimmunity ReviewsCitation Excerpt :The initial search strategy identified 73 studies including review articles (Fig. 1 and Supplementary Table 3) Through the screening of the abstracts and titles, 52 association studies relating to HLA-DRB1, HLA-DQA1 and/or HLA-DQB1 polymorphisms and susceptibility to pSS were left for data extraction. Twenty eight articles were excluded (Supplementary Table 4) and a total of 23 articles for HLA-Class II region were included in the final meta-analysis [9–16,18–19,27–39]. A total of 1166 cases and 6470 controls were analyzed.
New insights into the diagnosis and treatment of dry eye
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