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Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2 pp 643–651Cite as

A Unified Theory of the Role of the Ocular Surface in Dry Eye

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 438))

Abstract

Dry eye symptoms arise from a series of etiologies and are manifest in different patients with varying severity. The National Eye Institute/Industry Workshop on Clinical Trials in Dry Eyes, under the chairmanship of Dr. Michael A. Lemp, defined specific subtypes of dry eye in order to standardize clinical tests used in diagnosis and design of clinical studies.1 The use of artificial tears is palliative at best, resulting in a reduction of ocular surface eyelid shear forces and some symptomatic relief. Future research should focus on mechanistic endpoints. What causative factor(s) initiates the sequence of events resulting in the clinical symptoms suffered by the patient?

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Author information

Authors and Affiliations

  1. Allergan, Inc., Irvine, California, USA

    Michael E. Stern & Jianping Gao

  2. Louisiana State University Eye Center, New Orleans, Louisiana, USA

    Roger W. Beuerman

  3. Scripps Research Foundation, La Jolla, California, USA

    Robert I. Fox

  4. University of Southern California, Los Angeles, California, USA

    Austin K. Mircheff

  5. University of Miami, Miami, Florida, USA

    Stephen C. Pflugfelder

Authors
  1. Michael E. Stern
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  2. Roger W. Beuerman
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  3. Robert I. Fox
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  4. Jianping Gao
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  5. Austin K. Mircheff
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  6. Stephen C. Pflugfelder
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Editor information

Editors and Affiliations

  1. The Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, USA

    David A. Sullivan  & Darlene A. Dartt  & 

  2. Louisiana State University Medical Center, New Orleans, Louisiana, USA

    Michele A. Meneray

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© 1998 Springer Science+Business Media New York

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Stern, M.E., Beuerman, R.W., Fox, R.I., Gao, J., Mircheff, A.K., Pflugfelder, S.C. (1998). A Unified Theory of the Role of the Ocular Surface in Dry Eye. In: Sullivan, D.A., Dartt, D.A., Meneray, M.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology, vol 438. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5359-5_91

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  • DOI: https://doi.org/10.1007/978-1-4615-5359-5_91

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7445-9

  • Online ISBN: 978-1-4615-5359-5

  • eBook Packages: Springer Book Archive

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