Regular ArticleB Lymphocyte Stimulator Protein-Associated Increase in Circulating Autoantibody Levels May Require CD4+ T Cells: Lessons from HIV-Infected Patients☆
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2013, The Lancet Infectious DiseasesHigh expression levels of B lymphocyte stimulator (BLyS) by dendritic cells correlate with HIV-related B-cell disease progression in humans
2011, BloodCitation Excerpt :We now report that these mature mDCs are driven to excessive expression of surface BLyS, with a concomitant increase in blood levels of BLyS and B-cell growth factors. A previous study by Stohl et al has shown that BLyS expression levels by blood monocytes correlated with serum autoantibody titers in HIV-infected subjects.24 Our results have also demonstrated that blood monocytes from HIV-infected individuals express BLyS, but the level of expression was less elevated and sustained than that found on mDCs.
B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling
2007, Current Opinion in ImmunologyTargeting BAFF: Immunomodulation for autoimmune diseases and lymphomas
2006, Pharmacology and TherapeuticsHigh TNFSF13B expression as a predictor of poor prognosis in adrenocortical carcinoma
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To whom correspondence should be addressed at Division of Rheumatology, University of Southern California, 2011 Zonal Avenue, HMR 711, Los Angeles, CA 90033. Fax: (323) 442-2874. E-mail: [email protected].