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In an article published in the Annals of the Rheumatic Diseases, Schönau et al suggested that positron emitted tomography (PET)/CT is useful in determining the cause of unexplained fever/inflammation.1 In this letter, we wish to add further data to support the conclusions of this article. More and more, PET/CT is used to determine the cause of fever, systemic inflammation or atypical or resistant rheumatic disease. However, the utility of PET/CT in these diagnoses is not clear. Thus, we performed a meta-analysis to investigate the utility of PET/CT in the diagnosis of inflammatory rheumatic diseases.
We searched MEDLINE to identify all reports of interest published prior to June 2016 using the search terms: ‘(PET scan OR …
Footnotes
Contributors LD, MS and SM were responsible for the study concept and design and drafting the manuscript. LD, LO and SM were involved in the acquisition of data. LD, LO, MS and SM were responsible for the analysis and interpretation of data. LD and SM did the statistical analysis. SM had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis and was involved in the supervision of the study. All the authors equally contributed to the critical revision of the manuscript for important intellectual content.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.