Systemic Sclerosis

  • Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk
    Aida Moreno-Moral, Marta Bagnati, Surya Koturan, Jeong-Hun Ko, Carmen Fonseca, Nathan Harmston, Laurence Game, Javier Martin, Voon Ong, David J Abraham, Christopher P Denton, Jacques Behmoaras, Enrico Petretto
  • Protein kinases G are essential downstream mediators of the antifibrotic effects of sGC stimulators
    Alexandru-Emil Matei, Christian Beyer, Andrea-Hermina Györfi, Alina Soare, Chih-Wei Chen, Clara Dees, Christina Bergmann, Andreas Ramming, Andreas Friebe, Franz Hofmann, Oliver Distler, Georg Schett, Jörg H W Distler
  • Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study
    Ariane L Herrick, Sebastien Peytrignet, Mark Lunt, Xiaoyan Pan, Roger Hesselstrand, Luc Mouthon, Alan J Silman, Graham Dinsdale, Edith Brown, László Czirják, Jörg H W Distler, Oliver Distler, Kim Fligelstone, William J Gregory, Rachel Ochiel, Madelon C Vonk, Codrina Ancuţa, Voon H Ong, Dominique Farge, Marie Hudson, Marco Matucci-Cerinic, Alexandra Balbir-Gurman, Øyvind Midtvedt, Paresh Jobanputra, Alison C Jordan, Wendy Stevens, Pia Moinzadeh, Frances C Hall, Christian Agard, Marina E Anderson, Elisabeth Diot, Rajan Madhok, Mohammed Akil, Maya H Buch, Lorinda Chung, Nemanja S Damjanov, Harsha Gunawardena, Peter Lanyon, Yasmeen Ahmad, Kuntal Chakravarty, Søren Jacobsen, Alexander J MacGregor, Neil McHugh, Ulf Müller-Ladner, Gabriela Riemekasten, Michael Becker, Janet Roddy, Patricia E Carreira, Anne Laure Fauchais, Eric Hachulla, Jennifer Hamilton, Murat İnanç, John S McLaren, Jacob M van Laar, Sanjay Pathare, Susanna M Proudman, Anna Rudin, Joanne Sahhar, Brigitte Coppere, Christine Serratrice, Tom Sheeran, Douglas J Veale, Claire Grange, Georges-Selim Trad, Christopher P Denton
  • Scleroderma fibroblasts suppress angiogenesis via TGF-β/caveolin-1 dependent secretion of pigment epithelium-derived factor
    Vasiliki Liakouli, Jacobo Elies Comez, Yasser Mohamed El-Sherbiny, Margherita Scarcia, Gary Grant, Giuseppina Abignano, Emma C Derrett-Smith, Filomena Esteves, Paola Cipriani, Paul Emery, Christopher P Denton, Roberto Giacomelli, Georgia Mavria, Francesco Del Galdo
  • Factors associated with disease progression in early-diagnosed pulmonary arterial hypertension associated with systemic sclerosis: longitudinal data from the DETECT cohort
    Carina Mihai, Milos Antic, Rucsandra Dobrota, Diana Bonderman, Harbajan Chadha-Boreham, John Gerry Coghlan, Christopher P Denton, Martin Doelberg, Ekkehard Grünig, Dinesh Khanna, Vallerie V McLaughlin, Ulf Müller-Ladner, Janet E Pope, Daniel M Rosenberg, James R Seibold, Madelon C Vonk, Oliver Distler
  • The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis
    Christina Bergmann, Amelie Brandt, Benita Merlevede, Ludwig Hallenberger, Clara Dees, Thomas Wohlfahrt, Sebastian Pötter, Yun Zhang, Chih-Wei Chen, Tatiana Mallano, Ruifang Liang, Rosebeth Kagwiria, Alexander Kreuter, Ioanna Pantelaki, Aline Bozec, David Abraham, Ralf Rieker, Andreas Ramming, Oliver Distler, Georg Schett, Jörg H W Distler
  • Mapping and predicting mortality from systemic sclerosis
    Muriel Elhai, Christophe Meune, Marouane Boubaya, Jérôme Avouac, Eric Hachulla, Alexandra Balbir-Gurman, Gabriela Riemekasten, Paolo Airò, Beatriz Joven, Serena Vettori, Franco Cozzi, Susanne Ullman, László Czirják, Mohammed Tikly, Ulf Müller-Ladner, Paola Caramaschi, Oliver Distler, Florenzo Iannone, Lidia P Ananieva, Roger Hesselstrand, Radim Becvar, Armando Gabrielli, Nemanja Damjanov, Maria J Salvador, Valeria Riccieri, Carina Mihai, Gabriella Szücs, Ulrich A Walker, Nicolas Hunzelmann, Duska Martinovic, Vanessa Smith, Carolina de Souza Müller, Carlo Maurizio Montecucco, Daniela Opris, Francesca Ingegnoli, Panayiotis G Vlachoyiannopoulos, Bojana Stamenkovic, Edoardo Rosato, Stefan Heitmann, Jörg H W Distler, Thierry Zenone, Matthias Seidel, Alessandra Vacca, Ellen De Langhe, Srdan Novak, Maurizio Cutolo, Luc Mouthon, Jörg Henes, Carlo Chizzolini, Carlos Alberto von Mühlen, Kamal Solanki, Simona Rednic, Lisa Stamp, Branimir Anic, Vera Ortiz Santamaria, Maria De Santis, Sule Yavuz, Walter Alberto Sifuentes-Giraldo, Emmanuel Chatelus, Jiri Stork, Jacob van Laar, Esthela Loyo, Paloma García de la Peña Lefebvre, Kilian Eyerich, Vanesa Cosentino, Juan Jose Alegre-Sancho, Otylia Kowal-Bielecka, Grégoire Rey, Marco Matucci-Cerinic, Yannick Allanore
  • Pan-PPAR agonist IVA337 is effective in experimental lung fibrosis and pulmonary hypertension
    Jerome Avouac, Irena Konstantinova, Christophe Guignabert, Sonia Pezet, Jeremy Sadoine, Thomas Guilbert, Anne Cauvet, Ly Tu, Jean-Michel Luccarini, Jean-Louis Junien, Pierre Broqua, Yannick Allanore
  • Update of EULAR recommendations for the treatment of systemic sclerosis
    Otylia Kowal-Bielecka, Jaap Fransen, Jerome Avouac, Mike Becker, Agnieszka Kulak, Yannick Allanore, Oliver Distler, Philip Clements, Maurizio Cutolo, Laszlo Czirjak, Nemanja Damjanov, Francesco del Galdo, Christopher P Denton, Jörg H W Distler, Ivan Foeldvari, Kim Figelstone, Marc Frerix, Daniel E Furst, Serena Guiducci, Nicolas Hunzelmann, Dinesh Khanna, Marco Matucci-Cerinic, Ariane L Herrick, Frank van den Hoogen, Jacob M van Laar, Gabriela Riemekasten, Richard Silver, Vanessa Smith, Alberto Sulli, Ingo Tarner, Alan Tyndall, Joep Welling, Frederic Wigley, Gabriele Valentini, Ulrich A Walker, Francesco Zulian, Ulf Müller-Ladner
  • Development and validation of a patient-reported outcome instrument for skin involvement in patients with systemic sclerosis
    Ada Man, Jeannette K Correa, Jessica Ziemek, Robert W Simms, David T Felson, Robert Lafyatis

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