Systemic Sclerosis

  • Inhibition of phosphodiesterase 4 (PDE4) reduces dermal fibrosis by interfering with the release of interleukin-6 from M2 macrophages
    Christiane Maier, Andreas Ramming, Christina Bergmann, Rita Weinkam, Nicolai Kittan, Georg Schett, Jörg H W Distler, Christian Beyer
  • Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis
    Chikashi Terao, Takahisa Kawaguchi, Philippe Dieude, John Varga, Masataka Kuwana, Marie Hudson, Yasushi Kawaguchi, Marco Matucci-Cerinic, Koichiro Ohmura, Gabriela Riemekasten, Aya Kawasaki, Paolo Airo, Tetsuya Horita, Akira Oka, Eric Hachulla, Hajime Yoshifuji, Paola Caramaschi, Nicolas Hunzelmann, Murray Baron, Tatsuya Atsumi, Paul Hassoun, Takeshi Torii, Meiko Takahashi, Yasuharu Tabara, Masakazu Shimizu, Akiko Tochimoto, Naho Ayuzawa, Hidetoshi Yanagida, Hiroshi Furukawa, Shigeto Tohma, Minoru Hasegawa, Manabu Fujimoto, Osamu Ishikawa, Toshiyuki Yamamoto, Daisuke Goto, Yoshihide Asano, Masatoshi Jinnin, Hirahito Endo, Hiroki Takahashi, Kazuhiko Takehara, Shinichi Sato, Hironobu Ihn, Soumya Raychaudhuri, Katherine Liao, Peter Gregersen, Naoyuki Tsuchiya, Valeria Riccieri, Inga Melchers, Gabriele Valentini, Anne Cauvet, Maria Martinez, Tsuneyo Mimori, Fumihiko Matsuda, Yannick Allanore
  • Elevated serum levels of sonic hedgehog are associated with fibrotic and vascular manifestations in systemic sclerosis
    Christian Beyer, Dörte Huscher, Andreas Ramming, Christina Bergmann, Jerome Avouac, Serena Guiducci, Florian Meier, Serena Vettori, Elise Siegert, Veronika K Jaeger, Britta Maurer, Gabriela Riemekasten, Ulrich Walker, Ulf Müller-Ladner, Gabriele Valentini, Marco Matucci-Cerinic, Yannick Allanore, Oliver Distler, Georg Schett, Jörg H W Distler
  • Endothelial-to-mesenchymal transition contributes to endothelial dysfunction and dermal fibrosis in systemic sclerosis
    Mirko Manetti, Eloisa Romano, Irene Rosa, Serena Guiducci, Silvia Bellando-Randone, Amato De Paulis, Lidia Ibba-Manneschi, Marco Matucci-Cerinic
  • Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling
    Chih-Wei Chen, Christian Beyer, Jun Liu, Christiane Maier, Chun Li, Thuong Trinh-Minh, Xiaohan Xu, Stuart H Cole, Mindy H Hsieh, Nicholas Ng, Alana Althage, Shelly Meeusen, Shifeng Pan, Eric C Svensson, H Martin Seidel, Georg Schett, Peter Gergely, Jennifer L Harris, Jörg H W Distler
  • The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc
    Ruifang Liang, Barbora Šumová, Cinzia Cordazzo, Tatjana Mallano, Yun Zhang, Thomas Wohlfahrt, Clara Dees, Andreas Ramming, Dorota Krasowska, Małgorzata Michalska-Jakubus, Oliver Distler, Georg Schett, Ladislav Šenolt, Jörg H W Distler
  • 05.11 Antisense long noncoding rnas are deregulated in skin tissue of ssc patients
    Tobias Messemaker, Loubna Chadli, Varshna Goelela, Maaike Boonstra, Annemarie Dorjee, Stefan Andersen, Harald Mikkers, Oliver Distler, Tom Huizinga, Zhenghui Li, Guoshuai Cai, Michael Whitfield, Rene Toes, Jamil Aarbiou, Jeroen de Groot, Jeska De Vries-Bouwstra, Fina Kurreeman
  • Development and validation of a patient-reported outcome instrument for skin involvement in patients with systemic sclerosis
    Ada Man, Jeannette K Correa, Jessica Ziemek, Robert W Simms, David T Felson, Robert Lafyatis
  • Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS)
    Ariane L Herrick, Xiaoyan Pan, Sébastien Peytrignet, Mark Lunt, Roger Hesselstrand, Luc Mouthon, Alan Silman, Edith Brown, László Czirják, Jörg H W Distler, Oliver Distler, Kim Fligelstone, William J Gregory, Rachel Ochiel, Madelon Vonk, Codrina Ancuţa, Voon H Ong, Dominique Farge, Marie Hudson, Marco Matucci-Cerinic, Alexandra Balbir-Gurman, Øyvind Midtvedt, Alison C Jordan, Paresh Jobanputra, Wendy Stevens, Pia Moinzadeh, Frances C Hall, Christian Agard, Marina E Anderson, Elisabeth Diot, Rajan Madhok, Mohammed Akil, Maya H Buch, Lorinda Chung, Nemanja Damjanov, Harsha Gunawardena, Peter Lanyon, Yasmeen Ahmad, Kuntal Chakravarty, Søren Jacobsen, Alexander J MacGregor, Neil McHugh, Ulf Müller-Ladner, Gabriela Riemekasten, Michael Becker, Janet Roddy, Patricia E Carreira, Anne Laure Fauchais, Eric Hachulla, Jennifer Hamilton, Murat İnanç, John S McLaren, Jacob M van Laar, Sanjay Pathare, Susannah Proudman, Anna Rudin, Joanne Sahhar, Brigitte Coppere, Christine Serratrice, Tom Sheeran, Douglas J Veale, Claire Grange, Georges-Selim Trad, Christopher P Denton
  • Optical coherence tomography as a method for quantitative skin evaluation in systemic sclerosis
    Natália Sotero Machado Pires, Andréa Tavares Dantas, Angela Luzia Branco Pinto Duarte, Marcello Magri Amaral, Luana Osório Fernandes, Tereza Januária Costa Dias, Luciana Santos Afonso de Melo, Anderson Stevens Leônidas Gomes

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