SNP | Locus | M/m | MAF | OR (95% CI) | P values |
rs17581834 | IL19 | C/T | 0.12/0.05 | 2.7 (1.5 to 5.2) | 1.1×10−3 |
rs11119598 | IL19 | A/G | 0.11/0.05 | 2.5 (1.4 to 4.6) | 3.1×10−3 |
rs74148801 | IL19 | C/T | 0.11/0.05 | 2.6 (1.4 to 4.8) | 2.1×10−3 |
Logistic regression analysis between the three IL19 risk variants and stroke/MI in rheumatoid arthritis (genetic data available for 71 RA patients with and 753 without stroke/MI after RA-disease onset).
IL, interleukin; MAF, minor allele frequency for cases/controls; M/m, major/minor alleles; MI, myocardial infarction; P, p value unadjusted; SNP, single nucleotide polymorphism.