Table 2

VAS and LI

CSCelecoxibPlacebo
nMean (SE)*p Value†nMean (SE)*p Value†nMean (SE)*p Value‡
VAS
 Baseline19971.2 (0.8)19570.0 (0.8)20570.2 (0.8)
 Day 3019549.4 (1.5)0.86919546.9 (1.5)0.15920449.7 (1.4)0.309
 Day 9117939.4 (1.7)0.42918238.3 (1.7)0.21318841.2 (1.6)0.450
 Day 18216028.6 (1.8)0.00117330.5 (1.7)0.00917236.8 (1.7)0.002
LI
 Baseline19911.8 (0.2)19511.6 (0.2)20511.8 (0.2)
 Day 30195 9.6 (0.3)0.714195 9.1 (0.3)0.045204 9.8 (0.3)0.105
 Day 91179 8.1 (0.3)0.050182 8.0 (0.3)0.027188 8.8 (0.3)0.052
 Day 182160 7.1 (0.3)0.023173 7.0 (0.3)0.015172 8.0 (0.3)0.024
  • *Estimated mean and SE from a mixed-model analysis.

  • †Compared with placebo.

  • ‡Comparing three treatment groups.

  • LI, Lequesne Index; VAS, Visual Analogue Scale.