| Rituximab | Tocilizumab | Golimumab | Adalimumab | Abatacept | Etanercept |
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|
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| n=40 | n=42 | n=24 | n=42 | n=35 | n=39 |
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|
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DAS 28 | 4.3 vs 3.7 | 4.2 vs 2.8 | 4.1 vs 3.4 | 3.4 vs 2.8 | 4.3 vs 3.1 | 4.0 vs 2.8 |
| P 0.014 | P<0.001 | P 0.028 | P 0.011 | P<0.001 | P 0.0015 |
HAQ | 1.3 vs 1.1 | 1.0 vs 0.9 | 1.2 vs 1.0 | 1.7 vs 0.5 | 1.2 vs 1.0 | 1.1 vs 0.7 |
| | | | | | P<0.001 |
Swollen Joint Count | 3.8 vs 2.1 | 5.0 vs 1.8 | 5.3 vs 6.7 | 3.6 vs 1.7 | 3.7 vs 3.6 | 3.9 vs 1.7 |
| P 0.005 | P<0.001 | | P 0.010 | | P<0.001 |
AI | 4.0 vs 3.7 | 4.7 vs 4.0 | 3.2 vs 3.94 | 3.8 vs 3.7 | 4.1 vs 3.9 | 4.2 vs 3.7 |
| P 0.045 | | | | | |
10 yr CV Risk | 15.9 vs 17.9 | 13.5 vs 14.4 | 14 vs 15.7 | 10.1 vs 13.2 | 13.5 vs 14.1 | 11.2 vs 12.2 |
| | | | P 0.009 | | |