Table 1.

Performance of Sledai-2K to detect a clinically meaningful change in PGA, using cut-offs of decrease and increase (for a clinical improvement and worsening, respectively) in SLEDAI-2K ≥1 and ≥4 points

Δ SLEDAI-2K≥1Δ SLEDAI-2K≥4
Sens.Spec.PPVNPVSens.Spec.PPVNPV
Improvement PGA≥0.30.70.5710.3970.8250.2880.9290.6220.763
Worsening PGA≥0.30.7250.9030.6270.9360.3530.9960.9470.873
  • Sens: Sensitivity; Spec: Specificity; PPV: Positive predictive value; NPV: Non predictive value.