Table 1.

Status at the 1-year evaluation visit among patients with RA initiating a TNF inhibitor as their first ever biologic DMARD

EtanerceptInfliximabAdalimumabCertolizumabGolimumabP
N=1651N-1366N=1004N-921N=626
Observed percentage
 On drug70.666.469.265.268.0
 EULAR good response*28.023.925.924.327.8
 DAS28 remission*25.921.326.022.427.7
 HAQ improvement*28.024.529.025.024.8
 28 Joint counts = 0*23.316.820.419.021.6
Adjusted relative risk (95% CI)
 On drug Ref. 0.94 (0.89–1.00)0.98 (0.92–1.04)0.90 (0.84–0.96)0.97 (0.90–1.04)0.02
 EULAR good response* Ref. 0.82 (0.70–0.96)0.95 (0.80–1.12)0.84 (0.70–1.01)0.96 (0.79–1.17)0.10
 DAS28 remission* Ref. 0.83 (0.70–0.98)1.02 (0.85–1.21)0.89 (0.74–1.08)1.00 (0.82–1.23)0.12
 HAQ Improvement* Ref. 0.82 (0.70–0.96)1.04 (0.89–1.21)0.86 (0.73–1.03)0.86 (0.71–1.05)0.02
 28 Joint count = 0* Ref. 0.74 (0.61–0.89)0.91 (0.75–1.11)0.85 (0.69–1.04)0.91 (0.73–1.13)0.03
  • *LUNDEX corrected (1). Sex, age, disease duration, RF, co-treatment (methotrexate, glucocorticoids.)