Table 1

Gender	Age	Disease	Biologic therapy	Time with BT	Affection	Evolution until diagnosis	Treatment	Evolution

Man	35	Crohn disease	Adalimumab	4 years	Cutaneous	12 months	Intralesional injections of meglumine antimoniate	Resolution.
							EV liposomal amphotericin B.	Reintroduction of BT.
Woman	55	Crohn disease	Infliximab	3 years	Cutaneous	24 months	Intralesional injections of meglumine antimoniate	Resolution.
							EV liposomal amphotericin B.	Reintroduction of BT.
Man	61	Crohn disease	Adalimumab	3 years	Cutaneous and	5 months	EV liposomal amphotericin B	Resolution.
					hepatosplenomegaly			Reintroduction of BT.
Man	58	Psoriatic arthritis	Adalimumab	19 months	Cutaneous	8 months	EV liposomal amphotericin B	Resolution.
Man	51	Ankylosing spondylitis	Infliximab	12 years	Cutaneous	5 months	EV liposomal amphotericin B	Resolution.
								Reintroduction of BT.