Self-reported fatigue and depression at baseline, after treatment and at 6 months follow-up
| Scale | Mean (SD) t1 | Mean (SD) t2 | Mean (SD) t3 | P-value diff ANOVA | Paired t-test T1–3 |
|---|---|---|---|---|---|
| BRAF fatigue$ | 13.89 (5.4) | 10.85 (4.9) | 9.46 (5.8) | p>0.001 | Diff 4.57 (CI: 2.2/7.0) (p>0.001)** |
| PHQ# | 25.13 (5.9) | 20.67 (6.8) | 18.25 (7.1) | p>0.001 | Diff 6.44 (CI:4.0/8.9) (p>0.001)** |
| VAS pain† | 45.54 (24.4) | 39.08 (21.1) | 36.9 (23.0) | p>0.241 | Diff 7.64 (CI:-1.4/16.7) (p>0.096) |
$BRAF (Bristol Rheumatoid Arthritis Fatigue Multi-Dimensional questionnaire) fatigue global score (0–30), #PHQ-9 (Patient Health Questionnaire) depression score (0–70), †VAS pain (0–100).