Sociodemographic and clinical characteristics of Colombian patients with idiopathic inflammatory myopathy
| Polymyositis | Dermatomyositis | p-value | |||
|---|---|---|---|---|---|
| N=59 | N=53 | ||||
| N | % | N | % | ||
| Female | 41 | 69,5 | 35 | 66 | 0,69 |
| Age (mean) | 54,3 | 49,4 | 0,09 | ||
| Clinical characteristics | |||||
| Symmetrical muscle weakness | 59 | 100 | 51 | 96,2 | 0,13 |
| Gottron's papules | 0 | – | 49 | 92,4 | <0.0001 |
| Heliotrope rash | 0 | – | 35 | 66 | <0.0001 |
| Shawl sign/ V sign | 0 | – | 29 | 54,7 | <0.0001 |
| Polyautoimmunity | 11 | 18,6 | 3 | 5,6 | 0,03 |
| Muscle enzymes in serum | |||||
| CK (median) | 3825 | 1012 | 0,006 | ||
| LD (median) | 554 | 433 | 0,003 | ||
| ALT (median) | 87 | 46,3 | 0,01 | ||
| AST (median) | 72 | 38 | 0,005 | ||
| Aldolase | 8 | 13,5 | 5 | 9,4 | 0,43 |
| Autoantibodies | |||||
| ANA (+) | 27 | 45,7 | 38 | 71,7 | 0,0006 |
| Anti-Jo1 (+) | 2 | 3,4 | 2 | 3,8 | 0,74 |
| EMG | |||||
| Myophatic changes | 41 | 69,5 | 27 | 50,9 | 0,34 |
| Biopsy-proven myopathy | |||||
| Positive | 30 | 50,8 | 16 | 30,2 | 0,7 |
SES, socioeconomic status; CK, creatine phosphokinase; LD, lactate dehydrogenase; AST, aspartate transaminase; ALT, alanine transaminase; EMG, electromyogram.