Joint scores (mean ± SD)
| groups | 28d | 35d | 42d | 49d |
|---|---|---|---|---|
| a | o | o | o | o |
| b | 8.05±1.62 | 12.40±2.10 | 14.68±1.77 | 12.33±1.68 |
| c | 8.66±0.14 | 11.99±0.23 | 12.10±0.23** | 11.30±0.22** |
| d | 7.90±0.34 | 11.40±0.18 | 12.80±0.20** | 12.00±0.13 |
| e | 7.40±0.23 | 10.90±0.13* | 10.40±0.44** | 10.60±0.36** |
| f | 8.80±0.24 | 10.60±0.30* | 11.30±0.22** | 8.80±0.55** |
a. Blank group. b. Model group. c. Leflunomide group. d. Low-dose group. e. Medium-dose group. f. High-dose group. Compared with the model group, *p<0.05, **p<0.01.