Radiographic Progression of Structural Joint Damage for EXT Pts
| PBO/IXEQ4W (N=45) | PBO/IXEQ2W (N=46) | ADA/IXEQ4W (N=49) | ADA/IXEQ2W (N=48) | IXEQ4W/IXEQ4W (N=97) | IXEQ2W/IXEQ2W (N=96) | |
|---|---|---|---|---|---|---|
| Baseline (Week 0) Disease Characteristics, Mean (SD) | ||||||
| mTSS | 11.5 (15.5) | 24.5 (37.3) | 15.6 (24.3) | 15.4 (30.2) | 19.6 (33.3) | 15.2 (29.1) |
| Tender Joint Count | 18.5 (11.6) | 19.2 (14.0) | 18.8 (11.9) | 18.8 (12.8) | 20.8 (13.6) | 21.3 (13.8) |
| Swollen Joint Count | 9.6 (6.2) | 10.7 (7.1) | 10.1 (7.4) | 9.6 (5.5) | 11.0 (7.3) | 12.2 (7.3) |
| mTSS, Pre-Specified, Mean (SD) | ||||||
| Week 52 Change from Baseline | n=31 | n=37 | n=36 | n=34 | n=80 | n=80 |
| 0.27 (0.8) | 0.41 (0.8) | 0.32 (1.0) | -0.03 (0.4) | 0.54 (2.1) | 0.09 (1.0) | |
| mTSS, Post-Hoc, Mean (SD) | ||||||
| Week 52 Change from Baseline | n=44 | n=45 | n=47 | n=45 | n=97 | n=96 |
| 0.25 (0.8) | 0.51 (1.1) | 0.24 (0.9) | 0.06 (0.5) | 0.47 (1.9) | 0.09 (0.9) | |
N = EXT pts; n = pts with baseline and ≥1 post baseline radiograph assessments.