Table 1

Total, Direct and Indirect effects upon HAQ

Standardised effect upon HAQ	Females			Males

	Estimate	SE	p	Estimate	SE	p

DAS28 total	0.412	0.040	<0.001	0.508	0.053	<0.001
DAS28 indirect	0.139	0.024	<0.001	0.163	0.033	<0.001
DAS28- direct	0.282	0.046	<0.001	0.344	0.060	<0.001
DAS28 via pain and fatigue	0.038	0.010	<0.001	0.032	0.014	0.025
DAS28 via pain	0.101	0.024	<0.001	0.131	0.033	<0.001
Sobel test statistic (fatigue via pain)	3.280	0.002	0.001	2.279	0.002	0.022
Sobel test statistic (Pain)	3.920	0.085	<0.001	3.253	0.122	0.001

SE, standard error.