| – DO NOT prescribe NSAIDs to patients with high cardiovascular (CV) risk and particularly with hypertension. |
| – DO NOT prescribe NSAIDs to patients with CKD, heart failure or liver cirrhosis and, if necessary, exert caution. |
| – DO NOT use CV risk scores in patients who already suffered a CV event or those with multiple risk factors (smoking, obesity, sedentary lifestyle, DM, hypertension, dyslipidemia) or a family history of premature CV disease; All should be considered high CV risk. |
| – DO NOT base renal disease screening on a single glomerular filtration test and/or albuminuria (ALWAYS should be confirmed); serum creatinine should not be used as the only test to evaluate renal function. |
| – DO NOT administer biological therapy in case of active, serious and uncontrolled infection, sepsis or risk of sepsis or tuberculosis or without a previous screening of chronic HBV, HCV, HIV and TB. |
| – DO NOT repeat HBV vaccination unless HBV antibody levels are not achieved. |
| – DO NOT vaccinate a patient in therapy with biological agents or in immunosuppressive treatment with live viruses |