Maximum Total Bilirubin in Sarilumab-Treated Patients by rs6742078 Genotype
| Maximum total bilirubin, n (%) | |||
|---|---|---|---|
| Genotype, n (%) | ≤1.5×ULN | >1.5×ULN | Total |
| GG/GT | 352 (92) | 4 (27) | 356 (90) |
| TT | 29 (8) | 11 (73)a | 40 (10) |
| 381 | 15 | 396 | |
OR=34.7b; p=1.2×10-8. aElevations remained ≤2×ULN. bLogistic regression with recessive genetic model, adjusting for ancestry covariates.