Table 1.

Degrees of changes in serum uric acid levels by hormone replacement therapy type

	Estrogen mono		Estrogen-progestogen		Tibolone		Control

	Δ uric acid	P	Δ uric acid	P	Δ uric acid	P	Δ uric acid

Crude	0.64±0.26	1.000	-0.50±0.17	<0.001	0.16±0.18	0.097	0.67±0.13
Model I	0.63±0.26	0.994	-0.51±0.17	<0.001	0.15±0.18	0.059	0.71±0.13
Model II	0.63±0.26	0.994	-0.51±0.17	<0.001	0.14±0.18	0.060	0.71±0.13
Model III	0.67±0.27	0.988	-0.42±0.19	<0.001	0.30±0.21	0.206	0.77±0.14
Model IV	0.64±0.34	0.986	-0.47±0.29	<0.001	0.23±0.26	0.195	0.74±0.26
Model V	0.85±0.35	1.000	-0.41±0.29	<0.001	0.26±0.27	0.096	0.86±0.27

All models that included crude values were adjusted for follow-up intervals. Model I: adjusted age. Model II: adjusted age and BMI. Model III: adjusted age, BMI, HTN, DM, and dyslipidemia. Model IV: adjusted age, BMI, HTN, DM, dyslipidemia, alcohol consumption, and smoking status. Model V: adjusted age, BMI, HTN, DM, dyslipidemia, alcohol consumption, smoking status and co-medications.