Patient characteristics
| OA phenotype | arcOGEN_Illum610K N (men/women) | arcOGEN_OmniExpress N (men/women) | N total (men/women) | Prevalence (%) |
|---|---|---|---|---|
| Hip (KL Score ≥2) | 1817 (776/1041) | 301 (125/176) | 2118 (901/1217) | 100 |
| Site of maximal joint space narrowing (pattern of femoral head migration within the acetabulum) | ||||
| Axial | 158 (34/124) | 28 (5/23) | 186 (39/147) | 8.8 |
| Medial | 267 (69/198) | 48 (10/38) | 315 (79/236) | 14.9 |
| Superior | 1265 (615/650) | 204 (98/106) | 1469 (713/756) | 69.3 |
| Concentric | 127 (58/69) | 21(12/9) | 148 (70/78) | 7.0 |
| Bone remodelling response | ||||
| Atrophic | 267 (113/154) | 18* (8/10) | 285 (121/164) | 13.4 |
| Hypertrophic | 531 (239/292) | 106 (46/60) | 637 (285/352) | 30.1 |
| Normotrophic | 1019 (424/595) | 177(71/106) | 1196(495/701) | 56.5 |
*These individuals were not used as cases in the within-OA genome-wide association analysis of the arcOGEN OmniExpress data set due to the small sample number.
KL, Kellgren-Lawrence; OA, osteoarthritis.