TCZ-washout samples by TCZ concentration (SUMMACTA)
| Total: 928 total samples from 879 patients | TCZ BLQ | TCZ <10 μg/mL | TCZ ≥10 μg/mL |
|---|---|---|---|
| Washout samples, n (%)* | 549 (59.2) | 239 (25.8) | 140 (15.1) |
| Patients, n | 503 | 238 | 138 |
| Total patients who developed ADAs, n (%)† | 1 (0.2) | 1 (0.4) | 1 (0.7) |
| Positive neutralisation assay† | 0 | 0 | 1 (0.7) |
| Positive IgE assay | 0 | 0 | 0 |
Note: Multiple samples (with different TCZ concentrations) could be provided by a single patient.
*Denominator is total sample number.
†Denominator is total number of patients who provided washout samples.
ADA, antidrug antibody; BLQ, below the lower limit of quantitation (TCZ concentration, 100 ng/mL); TCZ, tocilizumab.