Table 3

Axial inflammatory symptoms, extra-articular manifestations and family history in PsSpA (n=127), AS (n=157) and pPsA (n=118) cases

	PsSpA	AS	pPsA	AS versus PsSpA			pPsA versus PsSpA
	n (%)	n (%)	n (%)	OR_adj	95% CI	p Value	OR_adj	95% CI	p Value
Inflammatory axial symptoms
Current
Spine or buttocks	65 (55)	133 (85)	54 (43)	2.76	1.62 to 4.71	<0.001*	0.57	0.34 to 0.96	0.03*
Ever (past/current)
Spine or buttocks	88 (75)	156 (99)	77 (61)	28.45	3.65 to 221.74	0.001*	0.69	0.38 to 1.25	0.22*
Cervical	71 (60)	132 (84)	54 (43)	1.82	0.94 to 3.55	0.08*	0.73	0.42 to 1.27	0.26*
Thoracic	50 (42)	114 (73)	27 (21)	2.20	1.23 to 3.92	0.01*	0.48	0.26 to 0.88	0.02*
Lumbar	70 (59)	149 (95)	58 (46)	6.75	2.82 to 16.16	<0.001*	0.82	0.47 to 1.43	0.48*
Buttocks	55 (47)	132 (84)	24 (19)	3.19	1.67 to 6.07	<0.001*	0.38	0.20 to 0.71	0.003*
Extra-articular manifestations (ever)
Dactylitis	37 (31)	8 (5)	50 (39)	0.18	0.07 to 0.42	<0.001*	1.09	0.62 to 1.93	0.76*
Enthesitis	56 (47)	58 (37)	59 (46)	0.70	0.43 to 1.14	0.15*	0.93	0.56 to 1.55	0.79*
Chest wall pain	52 (44)	102 (65)	34 (27)	1.21	0.70 to 2.19	0.52*	0.63	0.35 to 1.15	0.13*
Uveitis	31 (26)	84 (54)	11 (9)	1.44	0.79 to 2.62	0.24*	0.52	0.22 to 1.22	0.13*
Inflammatory bowel disease	13 (11)	15 (10)	2 (2)	0.85	0.36 to 1.98	0.70*	0.12	0.03 to 0.55	0.01*
Family history
Spondyloarthritis	25 (21)	52 (33)	16 (13)	1.26	0.67 to 2.34	0.47†	0.73	0.34 to 1.53	0.40†
Psoriasis	58 (49)	20 (13)	56 (44)	0.16	0.08 to 0.30	<0.001	0.79	0.46 to 1.36	0.40
Uveitis	7 (6)	37 (24)	4 (3)	2.27	0.94 to 5.51	0.07†	1.84	0.42 to 7.99	0.42†
Inflammatory bowel disease	9 (8)	17 (11)	11 (9)	1.57	0.59 to 4.17	0.37	1.10	0.42 to 2.90	0.84

*Multivariable reverse-stepwise logistic regression model (adjusted for potential covariates, including: sex, age at assessment, disease duration at assessment, HLA-B*27 status, synthetic DMARD use ever, anti-TNF use ever, smoking ever and body mass index).
†Reverse-stepwise logistic regression model adjusted for HLA-B*27 status.
Anti-TNF, antitumour necrosis factor; AS, ankylosing spondylitis; DMARD, disease modifying antirheumatic drug; n, proportion; OR_adj, adjusted OR; pPsA, peripheral psoriatic arthritis; PsSpA, psoriatic spondyloarthropathy.