Summary of baseline imbalances of biliary risk factors in the total study population
| Biliary risk factor | Summary results* |
|---|---|
| Age | Age ≥40 years is 2.1% more prevalent in SB4 over ETN |
| Sex | Female sex is 2.3% more prevalent in ETN over SB4 |
| BMI | SB4 has more obese patients† than ETN (27.8% vs 21.5%) |
| Hypertension | SB4 12.6% higher prevalence over ETN |
| Diabetes | SB4 16.9% higher prevalence over ETN |
| Dyslipidaemia | SB4 24.2% higher prevalence over ETN |
| Coronary artery disease | SB4 35.9% higher prevalence over ETN |
| Hypothyroidism | ETN 22.2% higher prevalence over SB4 |
| Prior bile stone history | ETN 11.7% higher prevalence over SB4 |
| Corticosteroid use | ETN and SB4 are almost similar (165 vs 168 patients) |
| Thiazide use | SB4 58.9% higher use over ETN |
*“over” means risk ratio of patients (eg, SB4: ETN patient incidence ratio or vice versa).
†Defined as BMI ≥30 kg/m2.
BMI, body mass index; ETN, etanercept.