Tabel 1. Characteristics of patients and controls
| SpA (n=34) | Control (n=57) | P-value | |
|---|---|---|---|
| Sex (% male) | 71% | 42% | <0.0001 (Fisher test) |
| Age (y) | 36.4 (33.3- 39.6) | 39.7 (35.8–43.6) | 0.13 (Unpaired t-test) |
| Smoker | 32% | 51% | 0.006 (Fisher test) |
| BMI (kg/m2) | 25.3 (23.7–26.9) | 25.6 (24.0–27.3) | 0.69 (Mann-Whitney test) |
| HLA-B27 | 82% | – | – |
| NSAID | 88% | – | – |
| Met11/Met11 | 8 (24%) | 21 (37%) | |
| Met11/Thr11 | 19 (58%) | 18 (32%) | |
| Thr11/Thr11 | 6 (18%) | 18 (32%) | |
| SP-D (ng/ml) | 1092 (725; 1541) | 910 (494; 1682) | 0.35 |
| H/L Mw SP-D ratio | 0.38 (0.18; 0.53) | 1.49 (0.37; 3.24) | 0.0004 |
Age, BMI: mean with 95% CI. SP-D and H/L Mw SP-D ratio: median with 25 and 75% percentile. Mann-Whitney test was used to compare SP-D levels and H/L Mw SP-D ratios.