NMR analyses (mean change from baseline ± SD)

	Wk 12

	PBO (N=488)	Bari (N=487)	ADA (N=330)

Total LDL particles^†	−22.4±236.1	15.0±282.3	−33.9±257.4*
Large LDL particles	−2.8±158.0	81.9±191.7***	42.2±182.2***
Small LDL particles	−21.3±285.8	−81.0±327.3***	−82.7±349.7***
Medium small LDL particles	−2.9±60.2	−16.6±67.6***	−15.5±74.4***
Very Small LDL particles	−18.5±228.7	−64.4±263.0***	−67.2±278.6***
Total HDL particles^§	−0.03±4.2	4.8±5.3***	2.0±4.6***
Large HDL particles	0.0±2.2	1.0±2.7***	0.4±2.2**
Medium HDL particles	0.1±2.8	0.7±3.5***	−0.4±3.1
Small HDL particles	−0.2±4.1	3.1±5.2***	2.0±4.3***
IDL particles^†	1.7±38.6	14.0±48.5***	6.6±40.4*
Total VLDL particles^†	−1.7±24.7	12.0±28.8***	6.1±23.8***
Large VLDL particles	−0.1±2.9	1.0±3.3***	0.5±2.7**
Medium VLDL particles	−0.8±15.7	5.5±18.2***	3.2±13.7***
Small VLDL particles	−0.8±15.0	5.6±17.1***	2.3±17.2*

^†Values for LDL and VLDL particles are nmol/L; ^§Values for HDL particles are μmol/L; Within-treatment p-values, *p≤0.05, **p≤0.01, ***p≤0.001.