Risk for development of lung cancer for different RA phenotypes
| Variable | Non-Smokers (never or ex-smokers) | Smokers (current) | ||
|---|---|---|---|---|
| N patients (seropositive with lung ca/total with lung ca) | RR (95% CI) | N patients (seropositive with lung ca/total with lung ca) | RR (95% CI) | |
| RF (pos vs neg) | 11/12 | 7.4 (1.0–57.4) | 17/20 | 2.4 (0.7–8.2) |
| ACPA (pos vs neg) | 9/12 | 2.3 (0.6–8.7) | 14/20 | 1.2 (0.4–3.1) |
| ACPA and/or RF pos vs double neg | 11/12 | 5.5 (0.7–42.5) | 19/20 | 5.8 (0.8–43.2) |
| Double pos (RF and ACPA) vs double neg | 9/10 | 6.1 (0.8–47.9) | 12/13 | 4.8 (0.6–36.5) |