Table 1.

Demographic features of FMF patients with amyloidosis

Male/Female40/39
Age of onset (mean ± SD, range)16±12 (2–68)
Age of diagnosis (mean ± SD, range)27±13 (7–70)
Family history of FMF47%
Disease follow-up duration (mo)66±85 (6–480)
Time to diagnosis (mo)121±136 (2–576)
Family history of amyloidosis (%)18%
Arthritis at presentation (%)60%
MEFV variations (n=46)M694V, 68%
V726A, 10%
M680I, 15%
Others, 7%
IL-1 inhibitors n (%)43 (54%)
Patients on hemodialysis7 (9%)
Renal Transplantation n (%)17 (21%)
High CRP levels in attack-free periods n (%)31 (39%)