Risk ratios (RR) and 95% CI compared to the German Childhood Cancer Registry report 2015 (1657/2056 cancers in children <15/<18 years of age in 10.5/12.9×106 children)
| Malignancies | N | RR (95% CI)* | P | |
|---|---|---|---|---|
| (Incidence/1000 PY) | (Wald test) | |||
| MTX <15 y (3224 PY) | All | 3 (0.93) | 5.90 (1.90–18.3) | 0.002 |
| Lymphoma & leukemia | 3 (0.93) | 13.74 (4.42–42.71) | <0.0001 | |
| ETA <15 (5333 PY) | All | 3 (0.56) | 3.56 (1.15–11.1) | 0.028 |
| Lymphoma & leukemia | 3 (0.56) | 8.31 (2.67–25.82) | 0.0003 | |
| MTX <18 y (4182 PY) | All | 3 (0.72) | 4.50 (1.45–13.97) | 0.009 |
| Lymphoma & leukemia | 3 (0.72) | 10.05 (3.23–31.21) | <0.0001 | |
| ETA <18 Y (6998 PY) | All | 9 (1.29) | 8.07 (4.19–15.53) | <0.0001 |
| Lymphoma & leukemia | 4 (0.57) | 8.01 (3.00–21.38) | <0.0001 | |