CRP, serum and faecal calprotectin according to bowel histology
| Marker | Median (range) normal biopsy | Median (range) bowel inflammation | p Value | Cut-off | Sens (%) | Spec (%) | Odds ratio for bowel inflammation | AUC (%) |
|---|---|---|---|---|---|---|---|---|
| CRP (mg/dl) | 0.4 (0–7.2) | 0.6 (0–10.5) | 0.036* | 0.4 | 67.3 | 54.4 | 2.46 (p=0.019) | 60.9 |
| Serum calpro (ng/mL) | 3022 (741–10 106) | 3948 (782–17 246) | 0.033* | 3340 | 60.4 | 61.1 | 2.4 (p=0.018) | 60.7 |
| Faecal calpro (µg/g) | 41 (0–1618) | 99 (14–513) | 0.036† | 85 | 64.3 | 73.3 | 4.95 (p=0.021) | 68.8 |
*Independent samples t test.
†Mann–Whitney U test.
AUC, area under the ROC curve; calpro, calprotectin (S100A8/S100A9); CRP, C-reactive protein; sens, sensitivity; spec, specificity.