Demographic and radiographic characteristics of individuals with erosive osteoarthritis compared to the reference groups with increasing grades of non-erosive radiographic hand osteoarthritis
| K&L≥3 | K&L=4 | Erosive osteoarthritis | |
|---|---|---|---|
| Number | n=193 | n=68 | n=80 |
| Age range, years | 52–91 | 55–85 | 51–87 |
| Mean age, years (SD) | 68.9 (8.1) | 69.1 (7.5) | 69.2 (7.8) |
| Female gender | 79.3% | 79.4% | 83.8% |
| Thumb IPJ osteoarthritis* | 63.7% | 69.1% | 68.8% |
| Thumb MCP osteoarthritis* | 14.0% | 16.2% | 23.8% |
| First CMC osteoarthritis* | 71.0% | 66.2% | 76.3% |
| Trapezioscaphoid joint osteoarthritis* | 30.6% | 27.9% | 29.1% |
| MCP osteoarthritis† | 30.6% | 35.3% | 32.5% |
| Symptomatic radiographic knee osteoarthritis‡ | 68.5% | 59.7% | 55.4% |
| Manual occupation | 56.3% | 56.5% | 48.6% |
| Attended higher education | 14.9% | 16.7% | 21.5% |
| Family history of arthritis | 68.4% | 63.2% | 71.2% |
| Previous hand injury | 25.4% | 24.6% | 32.9% |
| Excessive hand use at work or in pastimes | 77.6% | 76.2% | 83.8% |
| BMI>30 kg/m2 | 34.4% | 35.3% | 37.5% |
| Type 2 diabetes or impaired fasting glucose | 9.3% | 10.3% | 6.2% |
| Hypertension | 37.8% | 29.4% | 43.8% |
| Dyslipidaemia | 6.2% | 8.8% | 21.2% |
| Prescribed a lipid-regulating drug | 17.1% | 16.2% | 20.0% |
| Metabolic syndrome§ | 4.1% | 2.9% | 11.2% |
BMI, body mass index; CMC, carpometacarpal joint; IPJ, interphalangeal joint; K&L, Kellgren and Lawrence; MCP, metacarpophalangeal joint.
*Radiographic osteoarthritis determined by presence of K&L≥2.
†Radiographic osteoarthritis determined by the presence of K&L≥2 in one or more joints in the joint group.
‡Symptomatic radiographic knee osteoarthritis of tibiofemoral or patella-femoral joints of either knee (K&L≥2 on posterior–anterior or skyline views or posterior or lateral osteophytes Burnett grade≥1 on the lateral views).
§Metabolic syndrome was defined as the presence of three or more of the following: BMI>30 kg/m2, hypertension, dyslipidaemia and type 2 diabetes or impaired fasting glucose.