Characteristics of fever episodes according to the age and disease onset
| Whole TRAPS population | Paediatric patients | Adults with paediatric onset | Adults with adult onset | |
|---|---|---|---|---|
| (n=158) | (n=53) | (n=70) | (n=35) | |
| Number of patients | Number (%) | Number (%) | Number (%) | Number (%) |
| Disease course | ||||
| Recurrent* | 139 (88) | 48 (91) | 57 (81) | 34 (97) |
| Continuous† | 11 (7) | 4 (8) | 6 (9) | 1 (3) |
| Continuous with flares | 8 (5) | 1 (2) | 7 (10) | 0 |
| Characteristics of the disease episodes | ||||
| Duration | ||||
| >14 days | 32 (25) | 10 (24) | 14 (24) | 8 (27) |
| 7–14 days | 55 (43) | 18 (43) | 26 (46) | 11 (37) |
| <7 days | 42 (33) | 14 (33) | 17 (29) | 11 (37) |
| Mean duration (days) | 10.8 | 10.7 | 10.9 | 10.9 |
| Mean number of episodes/year | 7.7 | 7.7 | 7.6 | 6.9 |
| Fever (>38°C) | 132 (84) | 48 (91) | 56 (80) | 28 (80) |
| Low-grade fever (<38°C) | 57 (36) | 16 (30) | 27 (39) | 14 (40) |
| Rigours/chills at fever onset | 48 (30) | 18 (34) | 25 (36) | 5 (14) |
| Pattern of attacks | ||||
| Irregular | 91 (58) | 32 (60) | 39 (56) | 20 (57) |
| Regular | 19 (12) | 14 (26) | 4 (6) | 1 (3) |
| Seasonal changes | 4 (2.5) | 1 (3) | 3 (4) | 0 |
| Triggers | 40 (25) | 15 (28) | 19 (27) | 6 (17) |
*Recurrent manifestations with disease-free intervals.
†Continuous/subchronic manifestations with possible episodic flares.