Specific effect of remission according to different definitions of remission on all-cause mortality
| Remission 1 | Remission 2 | Remission 3 | All-cause mortality | |
|---|---|---|---|---|
| Sw 51+Tn51=0 | Sw28+Tn28=0 | Sw28≤1 and Tn28≤1 | HR (95% CI)* | HR (95% CI)† |
| – | – | – | 1 | 1 |
| – | – | ✓ | 0.95 (0.70 to 1.29) | 1.01 (0.74 to 1.38) |
| – | ✓ | ✓ | 0.80 (0.52 to 1.23) | 0.81 (0.52 to 1.27) |
| ✓ | ✓ | ✓ | 0.70 (0.53 to 0.92) | 0.71 (0.53 to 0.94) |
*Adjusted for age and gender.
†Adjusted for age, gender, smoke, RF, previous and/or concurrent treatment with DMARDs, symptoms duration at baseline, swollen joints at baseline, CRP levels at baseline, HAQ at baseline and calendar year; based on multiple imputation of missing data.
CRP, C reactive protein; DMARD, disease modifying antirheumatic drug, HAQ, Health Assessment Questionnaire; RF, rheumatoid factor; Sw, swollen joint count; Tn, tender joint count.