Table 1

Data on COMPASS total and individual domain scores of patients with PSS and community controls

COMPASS score
COMPASS domainPSSControlsPSS vs controls*
Orthostatic intolerance12.5 (2.5–17.5)0.0 (0.0–12.5)<0.0001
Vasomotor0.0 (0.0–5.0)0.0 (0.0–0.0)<0.0001
Secretomotor7.5 (7.5–9.0)1.5 (0.0–4.5)<0.0001
Gastroparesis0.0 (0.0–1.7)0.0 (0.0–0.0)0.0001
Autonomic diarrhoea0.0 (0.0–8.0)2.0 (0.0–8.0)0.21
Constipation1.5 (0.0–3.0)1.5 (0.0–3.0)0.25
Bladder control2.0 (0.0–4.0)2.0 (0.0–2.0)0.0002
Pupil and focusing2.0 (1.0–3.0)0.5 (0.0–1.5)<0.0001
Sleep disorders1.5 (0.0–2.3)0.0 (0.0–1.5)<0.0001
Syncope0.0 (0.0–0.0)0.0 (0.0–0.0)0.35
COMPASS total35.5 (20.9–46.0)14.8 (4.4–30.2)<0.0001
Understatement1.7 (0.0–3.3)6.0 (2.0–8.0)<0.0001
Overstatement0.0 (0.0–1.8)0.0 (0.0–7.0)<0.0001
  • Values are median (IQR).

  • * Wilcoxon matched pairs test.

  • COMPASS, Composite Autonomic Symptom Scale; PSS, primary Sjögren's syndrome.