Factors to explain neonates' complications
| Characteristics | Univariate OR (95% CI) | Multivariate OR (95% CI) |
|---|---|---|
| SLE | 2.8 (0.9 to 8.7) | |
| Anticoagulants before pregnancy | 2.2 (1.01 to 4.8) | |
| Recurrent miscarriage | 0.8 (0.6 to 1.002) | |
| Doppler notch | 2.1 (0.8 to 5) | |
| Mother's lupus anticoagulant | 3.9 (1.2 to 12) | 3.9 (1.2 to 12.4) |
| Caesarean delivery | 1.8 (0.9 to 3.6) |
Neonates' complications were defined as the presence of one of the following features among: less than 37 weeks term, birth weight, birth height or the cranial perimeter at birth being less than the 10th percentile or greater than the 97th percentile, Apgar score less than 8, neonatal complications, or neuropsychological developmental abnormalities during follow-up. Factors analysed to predict the neonates' complications: the mother's previous antiphospholipid syndrome characteristics, number and type of previous obstetric events, associated SLE, type and number of antiphospholipid antibodies, treatments before and during pregnancy, Doppler data, as well as delivery mode and term.
SLE, systemic lupus erythematosus.