Collagen content, GAG content and collagen modifications in normal PTT, stage II PTT and FDLT from female patients
| Median (range) | p Value | |||||
|---|---|---|---|---|---|---|
| Normal PTT | Stage II PTT | FDLT | N PTT v StII PTT | N PTT v FDLT | StII PTT v FDLT | |
| Collagen and GAG (μg/mg dry weight) | ||||||
| Collagen | 649 (455–819) | 535 (113–1275) | 735 (133–1000) | nsd | nsd | nsd |
| GAG | 6.5 (5.0–15.6) | 13.5 (4.8–31.5) | 2.2 (0.8–13.2) | p<0.05 | p<0.001 | p<0.001 |
| Collagen modifications (mol/mol collagen) | ||||||
| Pentosidine | 4.2×10−3 (2.1–7.4) | 1.6×10−3 (0.3–4.2) | 5.8×10−3 (3.3–10.8) | p<0.05 | nsd | p<0.001 |
| OHPyr | 0.48 (0.26–0.59) | 0.38 (0.27–0.50) | 0.13 (0.05–0.24) | nsd | p<0.001 | p<0.001 |
| HLKNL | 0.30 (0.12–0.59) | 0.26 (0.14–0.77) | 0.27 (0.15–0.46) | nsd | nsd | nsd |
| HHL | 0.11 (0.09–0.14) | 0.11 (0.06–0.16) | 0.20 (0.16–0.26) | nsd | p<0.001 | p<0.001 |
| HLNL | 0.10 (0.06–0.17) | 0.11 (0.05–0.16) | 0.22 (0.11–0.33) | nsd | p<0.001 | p<0.001 |
FDLT, flexor digitorum longus tendon; GAG, glycosaminoglycan; N, normal; nsd, no significant difference; PTT, posterior tibialis tendon; StII, stage II. OHPyr, hydroxylysyl pyridinoline, HLKNL, hydroxylysino-5-ketonorleucine, HHL, histidinohydroxylysinonorleucine, HLNL, hydroxylysinonorleucine