Sensitivity and specificity of FOI and CE versus PDUS, GSUS and MRI (synovitis or tenosynovitis) as standards of reference along with 95% confidence intervals
| FOI | MRI S or T | PDUS | GSUS | |||
|---|---|---|---|---|---|---|
| Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | Specificity | |
| FOI CI | 51% (38/75) | 81% (182/225) | 67% (88/132) | 54% (358/661) | 56% (223/398) | 57% (227/395) |
| 41%; 60% | 72%; 89% | 58%; 76% | 49%; 59% | 50%; 62% | 51%; 64% | |
| FOI P1 | 27% (20/75) | 94% (209/223) | 33% (49/148) | 90% (736/814) | 22% (100/453) | 95% (482/509) |
| 10%; 43% | 89%; 98% | 21%; 45% | 87%; 94% | 15%; 29% | 92%; 97% | |
| FOI P2 | 72% (54/75) | 56% (127/225) | 72% (106/148) | 44% (361/814) | 68% (306/453) | 50% (256/509) |
| 63%; 81% | 46%; 67% | 62%; 81% | 40%; 49% | 62%; 73% | 45%; 56% | |
| FOI P3 | 47% (35/75) | 89% (201/225) | 60% (89/148) | 69% (561/814) | 51% (229/453) | 78% (396/509) |
| 36%; 58% | 83%; 95% | 50%; 71% | 63%; 75% | 43%; 58% | 72%; 84% | |
| Any phase (P1–P3) | 76% (57/75) | 54% (122/225) | 74% (110/148) | 42% (340/814) | 70% (318/453) | 48% (243/509) |
| 67%; 85% | 43%; 65% | 65%; 84% | 37%; 47% | 64%; 76% | 42%; 53% | |
| CE | 53% (39%; 67%) | 81% (76%; 87%) | 43% (31%; 54%) | 88% (83%; 92%) | 25% (18%; 31%) | 90% (86%; 94%) |
Any phase, positive in any phase; CE, clinical examination (swollen joints); CI, composite image; FOI, fluorescence optical imaging; GSUS, ultrasonography in greyscale mode; P1, phase 1; P2, phase 2; P3, phase 3; PDUS, ultrasonography in power Doppler mode; S, synovitis; T, tenosynovitis.