OA | NA | Whole joint | |||||||
---|---|---|---|---|---|---|---|---|---|
MRI | BL | 1 Year | p Value | BL | 1 Year | p Value | BL | 1 Year | p Value |
ThCtAB (mm) | |||||||||
Femur | 1.00±0.41 | 1.41±0.30 | 0.000 | 2.10±0.42 | 2.11±0.41 | 0.598 | 3.25±0.39 | 3.57±0.47 | 0.001 |
Tibia | 1.36±0.34 | 1.56±0.31 | 0.029 | 2.05±0.32 | 2.07±0.27 | 0.641 | |||
dABp (%) | |||||||||
Femur | 27.31±25.64 | 4.19±10.22 | 0.000 | 0.63±1.40 | 0.50±1.39 | 0.402 | 11.32±10.02 | 2.52±4.44 | 0.001 |
Tibia | 16.70±17.22 | 4.82±8.33 | 0.006 | 0.65±2.34 | 0.57±2.54 | 0.592 | |||
ThCcAB (mm) | |||||||||
Femur | 1.33±0.25 | 1.46±0.24 | 0.001 | 2.11±0.42 | 2.12±0.41 | 0.659 | 3.56±0.38 | 3.64±0.42 | 0.070 |
Tibia | 1.62±0.24 | 1.64±0.25 | 0.653 | 2.07±0.30 | 2.07±0.25 | 0.698 |
Primary structural outcome parameters: thickness of cartilage over total area of bone (ThCtAB) and the percentage area of denuded bone (dABp); secondary structural outcome parameter: thickness of cartilage over area of bone covered with cartilage (ThCcAB). Mean±SD values are presented.