Table 2

Multivariate regression models for BASDAI50 response and ASAS partial remission using variables with p<0.1 on univariate screening, stepwise selection and final selection of variables for both the ASSERT and the GO–RAISE datasets

ASSERTGO–RAISECombined
AllSelectFinalAllSelectFinalAllSelectFinalFinal category
Age√, x√, x√, x√, x√, x√, x√, x>/≤40 years
BASDAI score√, x√, x√, x
BASFI score√, x√, x√, x√, x√, x√, x√, x√, xTertiles
BASMI score√, xx√, x√, x
Cervical rotation√, x√, x√, xx
Intermalleolar distance√, x√, x√, x
Tragus to wall distance√, x√, x√, x
Enthesitis score√, x√, x√, xx√, x√, x√, x√, x0/≥1
CRP√, x√, x√, x√, x√, x√, x√, x√, xTertiles
PGA√, x√, x√, x
HLA-B27√, x√, x√, x√, x√, x√, x√, x+/−
Treatment√, x√, x√, x√, x√, x√, x√, x√, x√, xAnti-TNF/placebo
R20.40, 0.340.36, 0.270.37, 0.270.27, 0.240.23, 0.180.24, 0.220.29, 0.260.27, 0.250.28, 0.240.32, 0.28
ROC–AUC (95% CI)0.83, 0.840.81, 0.800.82, 0.800.77, 0.780.75, 0.740.75, 0.770.78, 0.790.77, 0.790.77, 0.780.80 (0.76–0.83), 0.77 (0.73–0.82)
  • R2 and the area under the receiver operating characteristics curve (ROC–AUC) are presented for the different models. √ represents Bath ankylosing spondylitis disease activity index (BASDAI) 50, x represents assessment of spondyloarthritis (ASAS) partial remission. R2 and ROC–AUC values are presented for BASDAI50 response, ASAS partial remission.

    CRP, C-reactive protein; PGA, patient global assessment.